Which of the following is NOT an SSRI?

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Multiple Choice

Which of the following is NOT an SSRI?

Explanation:
SSRI stands for selective serotonin reuptake inhibitor, a class of antidepressants that increase serotonin in the brain by blocking its reabsorption. Prozac (fluoxetine), Zoloft (sertraline), and Paxil (paroxetine) all share this mechanism, so they are SSRI medications. Bupropion, however, works differently: it mainly inhibits the reuptake of norepinephrine and dopamine, with little effect on serotonin, so it does not belong to the SSRI class. This is why it is the correct item for “not an SSRI.”

SSRI stands for selective serotonin reuptake inhibitor, a class of antidepressants that increase serotonin in the brain by blocking its reabsorption. Prozac (fluoxetine), Zoloft (sertraline), and Paxil (paroxetine) all share this mechanism, so they are SSRI medications. Bupropion, however, works differently: it mainly inhibits the reuptake of norepinephrine and dopamine, with little effect on serotonin, so it does not belong to the SSRI class. This is why it is the correct item for “not an SSRI.”

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