Which drug is the antidote for warfarin overdose?

Study for the CJE Open Check Test. Practice with flashcards and multiple choice questions, each question offers hints and explanations. Prepare for exam success!

Multiple Choice

Which drug is the antidote for warfarin overdose?

Explanation:
Warfarin works by blocking the recycling of vitamin K, which prevents the liver from making the vitamin K–dependent clotting factors II, VII, IX, and X. Giving vitamin K replenishes the body's stores, allowing the liver to resume producing these factors and thereby reversing the anticoagulant effect. This direct counteraction to the drug’s mechanism is why vitamin K is the antidote. In emergencies with active bleeding, fresh frozen plasma can provide clotting factors immediately, but it doesn’t address the underlying deficiency that warfarin creates. Protamine sulfate reverses heparin, not warfarin, and calcium gluconate isn’t used to reverse anticoagulation.

Warfarin works by blocking the recycling of vitamin K, which prevents the liver from making the vitamin K–dependent clotting factors II, VII, IX, and X. Giving vitamin K replenishes the body's stores, allowing the liver to resume producing these factors and thereby reversing the anticoagulant effect. This direct counteraction to the drug’s mechanism is why vitamin K is the antidote.

In emergencies with active bleeding, fresh frozen plasma can provide clotting factors immediately, but it doesn’t address the underlying deficiency that warfarin creates. Protamine sulfate reverses heparin, not warfarin, and calcium gluconate isn’t used to reverse anticoagulation.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy