Which consideration applies to Diphenoxylate/Atropine?

• A. Monitor electrolytes and avoid caffeine
• B. Requires preoperative fasting
• C. Causes diarrhea
• D. Has no notable precautions

Answer: (D)

Diphenoxylate/atropine is an antidiarrheal combination that slows gut motility, with atropine added mainly to deter abuse. Because it’s used for short-term symptom relief and doesn’t require special monitoring under routine use, there aren’t specific precautions like electrolyte monitoring or dietary restrictions that you’d routinely apply. Preoperative fasting isn’t needed, and the drug doesn’t inherently cause diarrhea. So, in the context of typical exam framing, saying there are no notable precautions best fits how this medication is viewed for general use.