In which conditions is Sargramostim (GM-CSF) commonly used?

• A. For dehydration
• B. For viral infections
• C. After a bone marrow transplant and in acute myeloid leukemia
• D. For chronic kidney disease

Answer: (C)

GM-CSF acts as a hematopoietic growth factor that stimulates the bone marrow to produce granulocytes and macrophages, helping neutrophil recovery after heavy chemotherapy or a bone marrow transplant. That’s why it’s commonly used after a bone marrow transplant and in treatment contexts like acute myeloid leukemia, where supporting the myeloid cell line can be important. It’s not used to treat dehydration, viral infections, or chronic kidney disease, since those conditions aren’t addressed by boosting neutrophil production.