Filgrastim (Neupogen) is commonly used to treat which condition?

• A. Fever management
• B. To stimulate platelet production
• C. Neutropenia and mobilization of stem cells for autologous transplant
• D. Treat bacterial infection

Answer: (C)

Filgrastim is a granulocyte colony-stimulating factor that boosts neutrophil production in the bone marrow and can mobilize hematopoietic stem cells into the bloodstream for collection. In practice, it’s used to treat chemotherapy-induced neutropenia, shortening the duration of low neutrophil counts and reducing infection risk, and to mobilize stem cells for harvesting before an autologous transplant. It does not directly treat fever or bacterial infections, and it doesn’t primarily increase platelets. So the best fit is neutropenia management and stem cell mobilization for autologous transplant.