Etanercept & Infliximab are examples of which drug category?

• A. Antacid medications
• B. Laxatives
• C. DMARD II drugs
• D. DMARD I drugs

Answer: (C)

Etanercept and infliximab are biologic agents that inhibit tumor necrosis factor (TNF), a key driver of inflammation in autoimmune diseases. In the DMARD classification, conventional synthetic DMARDs (DMARD I) are small-molecule drugs like methotrexate, hydroxychloroquine, sulfasalazine, and leflunomide. Biologic or targeted DMARDs (DMARD II) include anti-TNF agents such as etanercept and infliximab, among others that specifically interrupt immune pathways. Because these drugs are biologics that target a specific immune signal, they fit best under DMARD II. They are not antacids or laxatives.